BDBM50051590 CHEMBL3337524::US11071729, Compound 1

SMILES Clc1c(ccn(CC2CC2)c1=O)N1CCC(CC1)c1ccccc1

InChI Key InChIKey=XTKQMUCOLYVCST-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50051590   

TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Addex Pharmaceuticals

US Patent
LigandPNGBDBM50051590(CHEMBL3337524 | US11071729, Compound 1)
Affinity DataEC50:  295nMAssay Description:Measurement of mGluR2 positive allosteric modulatory activity of test compounds in membranes containing human mGluR2 was performed using frozen membr...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Addex Pharmaceuticals

US Patent
LigandPNGBDBM50051590(CHEMBL3337524 | US11071729, Compound 1)
Affinity DataEC50:  170nMAssay Description:Positive allosteric modulation of human mGlu2 receptor expressed in CHO cells assessed as potentiation of glutamate-induced effect incubated for 30 m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed