BDBM50052157 (2S,5R)-8-Methyl-3-p-tolyl-8-aza-bicyclo[3.2.1]octane-2-carboxylic acid phenyl ester::CHEMBL328597

SMILES CN1[C@@H]2CCC1[C@H](C(C2)c1ccc(C)cc1)C(=O)Oc1ccccc1

InChI Key InChIKey=HIQHQNWJRSNELD-GHOZHQTGSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50052157   

TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50052157((2S,5R)-8-Methyl-3-p-tolyl-8-aza-bicyclo[3.2.1]oct...)
Affinity DataIC50:  3.30nMAssay Description:Binding affinity against Dopamine transporter using [3H]WIN-35 428 in rat striatumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50052157((2S,5R)-8-Methyl-3-p-tolyl-8-aza-bicyclo[3.2.1]oct...)
Affinity DataIC50:  5.80E+3nMAssay Description:Binding affinity against Norepinephrine transporter using [3H]nisoxetine in midbrain of ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50052157((2S,5R)-8-Methyl-3-p-tolyl-8-aza-bicyclo[3.2.1]oct...)
Affinity DataIC50:  2.45E+4nMAssay Description:Binding affinity against serotonin transporter using [3H]paroxetine in rat frontal cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed