BDBM50052665 Adamantane-1-carboxylic acid (pyridin-3-ylmethyl)-amide::CHEMBL109347

SMILES O=C(NCc1cccnc1)C12CC3CC(CC(C3)C1)C2

InChI Key InChIKey=SIOCWTZRIYXTEE-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50052665   

TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Cancer Research Campaign Centre For Cancer Therapeutics

Curated by ChEMBL
LigandPNGBDBM50052665(Adamantane-1-carboxylic acid (pyridin-3-ylmethyl)-...)
Affinity DataIC50:  1.80E+4nMAssay Description:Inhibition of C17,20-lyase enzyme, cytochrome P450 17A1 in Human testicular microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
University Of Bath

Curated by ChEMBL
LigandPNGBDBM50052665(Adamantane-1-carboxylic acid (pyridin-3-ylmethyl)-...)
Affinity DataIC50:  676nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells assessed as conversion of [3H]cortisone to [3H]cortisol after 2 hrs by scintillation counti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Cancer Research Campaign Centre For Cancer Therapeutics

Curated by ChEMBL
LigandPNGBDBM50052665(Adamantane-1-carboxylic acid (pyridin-3-ylmethyl)-...)
Affinity DataIC50:  3.20E+3nMAssay Description:Inhibition of Cytochrome P450 19A1 in Human placental microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Cancer Research Campaign Centre For Cancer Therapeutics

Curated by ChEMBL
LigandPNGBDBM50052665(Adamantane-1-carboxylic acid (pyridin-3-ylmethyl)-...)
Affinity DataIC50:  7.00E+4nMAssay Description:Inhibition of 17-alpha-hydroxylase enzyme, cytochrome P450 17A1 of human testicular microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed