BDBM50052665 Adamantane-1-carboxylic acid (pyridin-3-ylmethyl)-amide::CHEMBL109347
SMILES O=C(NCc1cccnc1)C12CC3CC(CC(C3)C1)C2
InChI Key InChIKey=SIOCWTZRIYXTEE-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50052665
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Cancer Research Campaign Centre For Cancer Therapeutics
Curated by ChEMBL
Cancer Research Campaign Centre For Cancer Therapeutics
Curated by ChEMBL
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of C17,20-lyase enzyme, cytochrome P450 17A1 in Human testicular microsomesMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
University Of Bath
Curated by ChEMBL
University Of Bath
Curated by ChEMBL
Affinity DataIC50: 676nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells assessed as conversion of [3H]cortisone to [3H]cortisol after 2 hrs by scintillation counti...More data for this Ligand-Target Pair
TargetAromatase(Homo sapiens (Human))
Cancer Research Campaign Centre For Cancer Therapeutics
Curated by ChEMBL
Cancer Research Campaign Centre For Cancer Therapeutics
Curated by ChEMBL
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of Cytochrome P450 19A1 in Human placental microsomesMore data for this Ligand-Target Pair
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Cancer Research Campaign Centre For Cancer Therapeutics
Curated by ChEMBL
Cancer Research Campaign Centre For Cancer Therapeutics
Curated by ChEMBL
Affinity DataIC50: 7.00E+4nMAssay Description:Inhibition of 17-alpha-hydroxylase enzyme, cytochrome P450 17A1 of human testicular microsomesMore data for this Ligand-Target Pair