BDBM50053137 (1-Aminooxalyl-3-biphenyl-2-ylmethyl-2-ethyl-indolizin-8-yloxy)-acetic acid::CHEMBL332993
SMILES CCc1c(Cc2ccccc2-c2ccccc2)n2cccc(OCC(O)=O)c2c1C(=O)C(N)=O
InChI Key InChIKey=UWYANTZRSJRLJO-UHFFFAOYSA-N
Data 18 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 18 hits for monomerid = 50053137
Affinity DataIC50: 6nMAssay Description:Inhibition of recombinant human secretory phospholipase A2 (sPLA2), chromogenic screening assay.More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of human group IIA phospholipase A2 preincubated with compound for 10 mins followed by enzyme addition and measured after 30 mins by PC/DO...More data for this Ligand-Target Pair
Affinity DataIC50: 60nMAssay Description:Inhibition of human group2A phospholipase A2 fluorimetric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 150nMAssay Description:Inhibition of mouse group2A phospholipase A2 fluorimetric assayMore data for this Ligand-Target Pair
TargetGroup IID secretory phospholipase A2(Homo sapiens (Human))
University Of Washington
Curated by ChEMBL
University Of Washington
Curated by ChEMBL
Affinity DataIC50: >1.30E+3nMAssay Description:Inhibition of human group2D phospholipase A2 by [3H]oleic acid-labeled Escherichia coli membrane assayMore data for this Ligand-Target Pair
Affinity DataIC50: >1.60E+3nMAssay Description:Inhibition of mouse group2D phospholipase A2 fluorimetric assayMore data for this Ligand-Target Pair
TargetGroup IIE secretory phospholipase A2(Homo sapiens (Human))
University Of Washington
Curated by ChEMBL
University Of Washington
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of human group2E phospholipase A2 fluorimetric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 35nMAssay Description:Inhibition of mouse group2E phospholipase A2 fluorimetric assayMore data for this Ligand-Target Pair
TargetGroup IIF secretory phospholipase A2(Homo sapiens (Human))
University Of Washington
Curated by ChEMBL
University Of Washington
Curated by ChEMBL
Affinity DataIC50: >1.60E+3nMAssay Description:Inhibition of human group2F phospholipase A2 fluorimetric assayMore data for this Ligand-Target Pair
Affinity DataIC50: >1.60E+3nMAssay Description:Inhibition of mouse group2F phospholipase A2 fluorimetric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of human group2V phospholipase A2 fluorimetric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 170nMAssay Description:Inhibition of mouse group2V phospholipase A2 fluorimetric assayMore data for this Ligand-Target Pair
TargetGroup 10 secretory phospholipase A2(Homo sapiens (Human))
University Of Washington
Curated by ChEMBL
University Of Washington
Curated by ChEMBL
Affinity DataIC50: >1.60E+3nMAssay Description:Inhibition of human group2X phospholipase A2 fluorimetric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 900nMAssay Description:Inhibition of mouse group2X phospholipase A2 fluorimetric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 700nMAssay Description:Inhibition of human group1B phospholipase A2 fluorimetric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of mouse group1B phospholipase A2 fluorimetric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of human group IIA phospholipase A2 incubated for 30 mins by automatic plate reader analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibitory activity against recombinant human secretory phospholipase A2 (s-PLA2) by phosphatidylcholine/deoxycholate assay (PC/DOC).More data for this Ligand-Target Pair