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BDBM50053577 CHEMBL3326370

SMILES: CCn1c2nc(N)c(cc2c(=O)n(CC)c1=O)C(N)=O

InChI Key: InChIKey=RULFHTRXYPKNLX-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50053577   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Serine/threonine-protein kinase EEF2K


(Homo sapiens (Human))
BDBM50053577
PNG
(CHEMBL3326370)
Show SMILES CCn1c2nc(N)c(cc2c(=O)n(CC)c1=O)C(N)=O
Show InChI InChI=1S/C12H15N5O3/c1-3-16-10-7(11(19)17(4-2)12(16)20)5-6(9(14)18)8(13)15-10/h5H,3-4H2,1-2H3,(H2,13,15)(H2,14,18)
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Similars

Article
PubMed
n/an/a 1.00E+3n/an/an/an/an/an/a



The University of Texas at Austin

Curated by ChEMBL


Assay Description
Inhibition of human recombinant eEF-2K expressed in bacteria pre-incubated for 30 mins before adding peptide substrate and [gamma32P]ATP by scintilla...


Bioorg Med Chem 22: 4910-6 (2014)


Article DOI: 10.1016/j.bmc.2014.06.050
BindingDB Entry DOI: 10.7270/Q2XD139S
More data for this
Ligand-Target Pair