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BDBM50053583 CHEMBL3327225

SMILES: CCCn1c(=O)n(C2CC2)c2nc(N)c(cc2c1=O)C(N)=O

InChI Key: InChIKey=KNBMWPBPZFBGQW-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50053583   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Eukaryotic elongation factor 2 kinase


(Homo sapiens (Human))
BDBM50053583
PNG
(CHEMBL3327225)
Show SMILES CCCn1c(=O)n(C2CC2)c2nc(N)c(cc2c1=O)C(N)=O
Show InChI InChI=1S/C14H17N5O3/c1-2-5-18-13(21)9-6-8(11(16)20)10(15)17-12(9)19(14(18)22)7-3-4-7/h6-7H,2-5H2,1H3,(H2,15,17)(H2,16,20)
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Article
PubMed
n/an/a 930n/an/an/an/an/an/a



The University of Texas at Austin

Curated by ChEMBL


Assay Description
Inhibition of human recombinant eEF-2K expressed in bacteria pre-incubated for 30 mins before adding peptide substrate and [gamma32P]ATP by scintilla...


Bioorg Med Chem 22: 4910-6 (2014)


Article DOI: 10.1016/j.bmc.2014.06.050
BindingDB Entry DOI: 10.7270/Q2XD139S
More data for this
Ligand-Target Pair