BDBM50053690 CHEMBL3323082
SMILES Cn1cc(cn1)[C@]1(N[C@H](Cc2c1[nH]c1ccccc21)c1nc(c[nH]1)-c1ccc(F)cc1)c1cc(ccn1)C(O)=O
InChI Key InChIKey=UHWQSESKOKODEV-HLADLETHSA-N
Data 9 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 9 hits for monomerid = 50053690
Affinity DataIC50: 1.70nMAssay Description:Displacement of [125I]SS-14 from mouse SSTR3 expressed in CHO cells by TopCount analyzerMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 1.96E+4nMAssay Description:Inhibition of human ERG by MK-499 displacement binding analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 2.10nMAssay Description:Displacement of [125I]SS-14 from human SSTR3 expressed in CHO cells by TopCount analyzerMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [125I]SS-14 from human SSTR4 expressed in CHO cells by TopCount analyzerMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [125I]SS-14 from human SSTR5 expressed in CHO cells by TopCount analyzerMore data for this Ligand-Target Pair
Affinity DataIC50: 1.70nMAssay Description:Antagonist activity at human SSTR3 expressed in CHO cells assessed as cAMP level by fluorescence analysisMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [125I]SS-14 from human SSTR1 expressed in CHO cells by TopCount analyzerMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [125I]SS-14 from human SSTR2 expressed in CHO cells by TopCount analyzerMore data for this Ligand-Target Pair
Affinity DataIC50: 0.730nMAssay Description:Antagonist activity at mouse SSTR3 expressed in CHO cells assessed as cAMP level by fluorescence analysisMore data for this Ligand-Target Pair