BDBM50053834 CHEMBL413308::[1-(1-Benzyl-2-{2-hydroxy-2-[3-(3-trifluoromethyl-phenoxy)-phenyl]-ethylcarbamoyl}-2-oxo-ethylcarbamoyl)-3-methyl-butyl]-carbamic acid benzyl ester

SMILES CC(C)CC(NC(=O)OCc1ccccc1)C(=O)NC(Cc1ccccc1)C(=O)C(=O)NCC(O)c1cccc(Oc2cccc(c2)C(F)(F)F)c1

InChI Key InChIKey=MDMSJUTXKFAZPC-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50053834   

TargetCathepsin B(Bos taurus (bovine))
Georgia Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50053834(CHEMBL413308 | [1-(1-Benzyl-2-{2-hydroxy-2-[3-(3-t...)
Affinity DataKi:  120nMAssay Description:Inhibition of bovine cathepsin BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
Georgia Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50053834(CHEMBL413308 | [1-(1-Benzyl-2-{2-hydroxy-2-[3-(3-t...)
Affinity DataKi:  180nMAssay Description:Inhibition of the cysteine protease human Calpain 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-2 catalytic subunit(Homo sapiens (Human))
Georgia Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50053834(CHEMBL413308 | [1-(1-Benzyl-2-{2-hydroxy-2-[3-(3-t...)
Affinity DataKi:  450nMAssay Description:Compound was evaluated for the inhibition of Cysteine protease Calpain 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed