BDBM50054546 (Z)-2-Cyano-3-cyclopropyl-3-hydroxy-N-[4-(4-trifluoromethyl-thiazol-2-yl)-phenyl]-acrylamide::CHEMBL143458

SMILES FC(F)(F)c1csc(n1)-c1ccc(NC(=O)C(C#N)C(=O)C2CC2)cc1

InChI Key InChIKey=VUMSACFELULPDY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50054546   

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Rattus norvegicus (rat))
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50054546((Z)-2-Cyano-3-cyclopropyl-3-hydroxy-N-[4-(4-triflu...)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibitory concentration tested against enzyme dihydroorotate dehydrogenase in ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Mus musculus)
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50054546((Z)-2-Cyano-3-cyclopropyl-3-hydroxy-N-[4-(4-triflu...)
Affinity DataIC50:  5.00E+4nMAssay Description:Inhibitory concentration tested on enzyme dihydroorotate dehydrogenase in mouseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed