BDBM50054785 CHEMBL3318965

SMILES Fc1ccccc1Oc1cccn2c(nnc12)C1(CC1)c1ccc(Cl)cc1

InChI Key InChIKey=OUNKWLWWQCCPIP-UHFFFAOYSA-N

Data  1 IC50  1 EC50

PDB links: 1 PDB ID matches this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50054785   

Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL

LigandBDBM50054785(CHEMBL3318965)Copy SMILESCopy InChI

Affinity DataIC50:  0.700nMAssay Description:Inhibition of human recombinant 11beta-HSD-1 expressed in HEK293 EBNA cells using [3H]-cortisone and NADPH by scintillation proximity assayMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidPDBSimilars

In DepthDetails ArticlePubMedPDB3D Structure (crystal)
Copy BDB DOI

TargetNuclear receptor subfamily 1 group I member 2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL

LigandBDBM50054785(CHEMBL3318965)Copy SMILESCopy InChI

Affinity DataEC50:  1.10E+3nMAssay Description:Activation of PXR (unknown origin)More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidPDBSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI