BDBM50054798 (1S,2R)-2-(1-Amino-propyl)-1-phenyl-cyclopropanecarboxylic acid diethylamide::CHEMBL119554

SMILES CCC(N)[C@@H]1C[C@@]1(C(=O)N(CC)CC)c1ccccc1

InChI Key InChIKey=LFIMCYFWWBLEGS-XJIUDMAQSA-N

Data  4 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50054798   

TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50054798((1S,2R)-2-(1-Amino-propyl)-1-phenyl-cyclopropaneca...)
Affinity DataKi:  2.40E+4nMAssay Description:Inhibition of [3H]-paroxetine binding on serotonin transporter of rat cerebral cortical synaptic membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50054798((1S,2R)-2-(1-Amino-propyl)-1-phenyl-cyclopropaneca...)
Affinity DataKi:  2.40E+4nMAssay Description:Inhibition of [3H]-paroxetine binding on serotonin transporter of rat cerebral cortical synaptic membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50054798((1S,2R)-2-(1-Amino-propyl)-1-phenyl-cyclopropaneca...)
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of Serotonin transporter in cerebral cortical synaptic membrane of rats using [3H]-paroxetineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50054798((1S,2R)-2-(1-Amino-propyl)-1-phenyl-cyclopropaneca...)
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of Serotonin transporter in cerebral cortical synaptic membrane of rats using [3H]-paroxetineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2C(Rattus norvegicus (Rat))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50054798((1S,2R)-2-(1-Amino-propyl)-1-phenyl-cyclopropaneca...)
Affinity DataIC50:  5.10E+4nMAssay Description:Percentage inhibition of N-methyl-D-aspartic acid (NMDA) receptor produced by oocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2C(Rattus norvegicus (Rat))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50054798((1S,2R)-2-(1-Amino-propyl)-1-phenyl-cyclopropaneca...)
Affinity DataIC50:  2.20E+3nMAssay Description:Concentration required to inhibit of N-methyl-D-aspartic acid (NMDA) receptor produced by oocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed