BDBM50055114 4-(5,5-Dimethyl-8-thiophen-2-yl-5,6-dihydro-naphthalen-2-ylethynyl)-benzoic acid::CHEMBL147937

SMILES CC1(C)CC=C(c2cccs2)c2cc(ccc12)C#Cc1ccc(cc1)C(O)=O

InChI Key InChIKey=CSXNWQRUNINKML-UHFFFAOYSA-N

Data  3 Kd  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50055114   

TargetRetinoic acid receptor beta(Homo sapiens (Human))
Allergan

Curated by ChEMBL
LigandPNGBDBM50055114(4-(5,5-Dimethyl-8-thiophen-2-yl-5,6-dihydro-naphth...)
Affinity DataKd:  20nMAssay Description:Inhibition of [3H]-ATRA binding to baculovirus expressed Retinoic acid receptor RAR betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor beta(Homo sapiens (Human))
Allergan

Curated by ChEMBL
LigandPNGBDBM50055114(4-(5,5-Dimethyl-8-thiophen-2-yl-5,6-dihydro-naphth...)
Affinity DataEC50:  25nMAssay Description:Transcriptional activation in CV-1 cells expressing Retinoic acid receptor RAR betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor alpha(Homo sapiens (Human))
Allergan

Curated by ChEMBL
LigandPNGBDBM50055114(4-(5,5-Dimethyl-8-thiophen-2-yl-5,6-dihydro-naphth...)
Affinity DataKd:  129nMAssay Description:Inhibition of [3H]-ATRA binding to baculovirus expressed Retinoic acid receptor RAR alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor gamma(Homo sapiens (Human))
Allergan

Curated by ChEMBL
LigandPNGBDBM50055114(4-(5,5-Dimethyl-8-thiophen-2-yl-5,6-dihydro-naphth...)
Affinity DataKd:  104nMAssay Description:Inhibition of [3H]-ATRA binding to baculovirus expressed Retinoic acid receptor RAR gammaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed