BDBM50055391 2-(3-(2-amino-2-oxoacetyl)-1-benzyl-2-ethyl-1H-indol-4-yloxy)propanoic acid::2-(3-Aminooxalyl-1-benzyl-2-ethyl-1H-indol-4-yloxy)-propionic acid::CHEMBL148649

SMILES CCc1c(C(=O)C(N)=O)c2c(OC(C)C(O)=O)cccc2n1Cc1ccccc1

InChI Key InChIKey=WTPLMBCNINDFBY-UHFFFAOYSA-N

Data  16 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 16 hits for monomerid = 50055391   

TargetPhospholipase A2, membrane associated(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50055391(2-(3-(2-amino-2-oxoacetyl)-1-benzyl-2-ethyl-1H-ind...)
Affinity DataIC50:  11nMAssay Description:Inhibition of human nonpancreatic secretory Phospholipase A2 through chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGroup 10 secretory phospholipase A2(Mus musculus)
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50055391(2-(3-(2-amino-2-oxoacetyl)-1-benzyl-2-ethyl-1H-ind...)
Affinity DataIC50:  20nMAssay Description:Inhibition of mouse group2X phospholipase A2 fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A2(Homo sapiens (Human))
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50055391(2-(3-(2-amino-2-oxoacetyl)-1-benzyl-2-ethyl-1H-ind...)
Affinity DataIC50:  80nMAssay Description:Inhibition of human group1B phospholipase A2 fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A2(Mus musculus)
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50055391(2-(3-(2-amino-2-oxoacetyl)-1-benzyl-2-ethyl-1H-ind...)
Affinity DataIC50:  100nMAssay Description:Inhibition of mouse group1B phospholipase A2 fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A2, membrane associated(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50055391(2-(3-(2-amino-2-oxoacetyl)-1-benzyl-2-ethyl-1H-ind...)
Affinity DataIC50:  170nMAssay Description:Inhibition of human group2A phospholipase A2 fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A2, membrane associated(Mus musculus)
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50055391(2-(3-(2-amino-2-oxoacetyl)-1-benzyl-2-ethyl-1H-ind...)
Affinity DataIC50:  60nMAssay Description:Inhibition of mouse group2A phospholipase A2 fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGroup IID secretory phospholipase A2(Homo sapiens (Human))
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50055391(2-(3-(2-amino-2-oxoacetyl)-1-benzyl-2-ethyl-1H-ind...)
Affinity DataIC50:  120nMAssay Description:Inhibition of human group2D phospholipase A2 by [3H]oleic acid-labeled Escherichia coli membrane assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGroup IID secretory phospholipase A2(Mus musculus)
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50055391(2-(3-(2-amino-2-oxoacetyl)-1-benzyl-2-ethyl-1H-ind...)
Affinity DataIC50: >1.60E+3nMAssay Description:Inhibition of mouse group2D phospholipase A2 fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGroup IIE secretory phospholipase A2(Homo sapiens (Human))
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50055391(2-(3-(2-amino-2-oxoacetyl)-1-benzyl-2-ethyl-1H-ind...)
Affinity DataIC50:  9nMAssay Description:Inhibition of human group2E phospholipase A2 fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGroup IIE secretory phospholipase A2(Mus musculus)
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50055391(2-(3-(2-amino-2-oxoacetyl)-1-benzyl-2-ethyl-1H-ind...)
Affinity DataIC50:  140nMAssay Description:Inhibition of mouse group2E phospholipase A2 fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGroup IIF secretory phospholipase A2(Homo sapiens (Human))
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50055391(2-(3-(2-amino-2-oxoacetyl)-1-benzyl-2-ethyl-1H-ind...)
Affinity DataIC50:  90nMAssay Description:Inhibition of human group2F phospholipase A2 fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGroup IIF secretory phospholipase A2(Mus musculus)
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50055391(2-(3-(2-amino-2-oxoacetyl)-1-benzyl-2-ethyl-1H-ind...)
Affinity DataIC50:  470nMAssay Description:Inhibition of mouse group2F phospholipase A2 fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A2 group V(Homo sapiens (Human))
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50055391(2-(3-(2-amino-2-oxoacetyl)-1-benzyl-2-ethyl-1H-ind...)
Affinity DataIC50:  44nMAssay Description:Inhibition of human group2V phospholipase A2 fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A2 group V(Mus musculus)
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50055391(2-(3-(2-amino-2-oxoacetyl)-1-benzyl-2-ethyl-1H-ind...)
Affinity DataIC50:  57nMAssay Description:Inhibition of mouse group2V phospholipase A2 fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGroup 10 secretory phospholipase A2(Homo sapiens (Human))
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50055391(2-(3-(2-amino-2-oxoacetyl)-1-benzyl-2-ethyl-1H-ind...)
Affinity DataIC50:  22nMAssay Description:Inhibition of human group2X phospholipase A2 fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A2, membrane associated(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50055391(2-(3-(2-amino-2-oxoacetyl)-1-benzyl-2-ethyl-1H-ind...)
Affinity DataIC50:  13nMAssay Description:Inhibition of human nonpancreatic secretory Phospholipase A2 through DOC/PC assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed