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BDBM50056028 ((R)-5-Piperazin-1-yl-2,3-dihydro-benzo[1,4]dioxin-2-yl)-methanol::CHEMBL106413

SMILES: OC[C@@H]1COc2c(O1)cccc2N1CCNCC1

InChI Key: InChIKey=BOXCVCJOJXRNFC-SNVBAGLBSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50056028   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50056028
PNG
(((R)-5-Piperazin-1-yl-2,3-dihydro-benzo[1,4]dioxin...)
Show SMILES OC[C@@H]1COc2c(O1)cccc2N1CCNCC1
Show InChI InChI=1S/C13H18N2O3/c16-8-10-9-17-13-11(2-1-3-12(13)18-10)15-6-4-14-5-7-15/h1-3,10,14,16H,4-9H2/t10-/m1/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
59n/an/an/an/an/an/an/an/a



Solvay Pharma

Curated by ChEMBL


Assay Description
Binding affinity was evaluated by determining in vitro displacement of [3H]-8-OH-DPAT from the central 5-hydroxytryptamine 1A receptor recognition si...


J Med Chem 40: 300-12 (1997)


Article DOI: 10.1021/jm960496o
BindingDB Entry DOI: 10.7270/Q27W6B96
More data for this
Ligand-Target Pair
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat))
BDBM50056028
PNG
(((R)-5-Piperazin-1-yl-2,3-dihydro-benzo[1,4]dioxin...)
Show SMILES OC[C@@H]1COc2c(O1)cccc2N1CCNCC1
Show InChI InChI=1S/C13H18N2O3/c16-8-10-9-17-13-11(2-1-3-12(13)18-10)15-6-4-14-5-7-15/h1-3,10,14,16H,4-9H2/t10-/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
>1.00E+4n/an/an/an/an/an/an/an/a



Solvay Pharma

Curated by ChEMBL


Assay Description
In vitro displacement of [3H]-spiperone from Dopamine receptor D2 binding site in rat striatum.


J Med Chem 40: 300-12 (1997)


Article DOI: 10.1021/jm960496o
BindingDB Entry DOI: 10.7270/Q27W6B96
More data for this
Ligand-Target Pair