BDBM50056250 (6S,9S)-6-Mercaptomethyl-7-oxo-6,7,8,9,10,11,12,13,14,15-decahydro-5H-8-aza-benzocyclotridecene-9-carboxylic acid::CHEMBL149841

SMILES OC(=O)[C@@H]1CCCCCCc2ccccc2C[C@H](CS)C(=O)N1

InChI Key InChIKey=KSCNYKDWJTZFRI-CVEARBPZSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50056250   

TargetThermolysin(Bacillus thermoproteolyticus)
Novartis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50056250((6S,9S)-6-Mercaptomethyl-7-oxo-6,7,8,9,10,11,12,13...)
Affinity DataIC50:  4.10E+4nMAssay Description:Inhibitory concentration required to inhibit thermolysinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeprilysin(Homo sapiens (Human))
Novartis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50056250((6S,9S)-6-Mercaptomethyl-7-oxo-6,7,8,9,10,11,12,13...)
Affinity DataIC50:  224nMAssay Description:Inhibition of neutral endopeptidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThermolysin(Bacillus thermoproteolyticus)
Novartis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50056250((6S,9S)-6-Mercaptomethyl-7-oxo-6,7,8,9,10,11,12,13...)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibitory concentration required to inhibit thermolysin (TLN)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeprilysin(Homo sapiens (Human))
Novartis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50056250((6S,9S)-6-Mercaptomethyl-7-oxo-6,7,8,9,10,11,12,13...)
Affinity DataIC50:  27nMAssay Description:Inhibitory concentration required to inhibit neutral endopeptidase (NEP)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50056250((6S,9S)-6-Mercaptomethyl-7-oxo-6,7,8,9,10,11,12,13...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibitory concentration required to inhibit Angiotensin I converting enzyme (ACE)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed