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BDBM50056900 2-Carbamoylphenol::2-Carboxamidophenol::2-Hydroxybenzamide::CHEMBL27577::OHB::Salicylic Acid amide::o-Hydroxybenzamide

SMILES: NC(=O)c1ccccc1O

InChI Key: InChIKey=SKZKKFZAGNVIMN-UHFFFAOYSA-N

Data: 3 IC50  1 Kd

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50056900   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Human immunodeficiency virus type 1 integrase


(Human immunodeficiency virus 1)
BDBM50056900
PNG
(2-Carbamoylphenol | 2-Carboxamidophenol | 2-Hydrox...)
Show SMILES NC(=O)c1ccccc1O
Show InChI InChI=1S/C7H7NO2/c8-7(10)5-3-1-2-4-6(5)9/h1-4,9H,(H2,8,10)
PDB
MMDB

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Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



National Cancer Institute

Curated by ChEMBL


Assay Description
Inhibition of HIV-1 integrase enzyme


J Med Chem 40: 937-41 (1997)


Article DOI: 10.1021/jm960755+
BindingDB Entry DOI: 10.7270/Q2154G4R
More data for this
Ligand-Target Pair
Androgen Receptor


(Homo sapiens (human))
BDBM50056900
PNG
(2-Carbamoylphenol | 2-Carboxamidophenol | 2-Hydrox...)
Show SMILES NC(=O)c1ccccc1O
Show InChI InChI=1S/C7H7NO2/c8-7(10)5-3-1-2-4-6(5)9/h1-4,9H,(H2,8,10)
PDB
MMDB

NCI pathway
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KEGG

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Article
PubMed
n/an/a>1.00E+3n/an/an/an/an/an/a



University of Colorado

Curated by ChEMBL


Assay Description
Inhibition of 1.0 nM [3H]mibolerone binding to human androgen receptor of PC3/AR cell lysate


J Med Chem 46: 5258-70 (2003)


Article DOI: 10.1021/jm0303305
BindingDB Entry DOI: 10.7270/Q27D2VV7
More data for this
Ligand-Target Pair
Stromelysin-1


(Homo sapiens (human))
BDBM50056900
PNG
(2-Carbamoylphenol | 2-Carboxamidophenol | 2-Hydrox...)
Show SMILES NC(=O)c1ccccc1O
Show InChI InChI=1S/C7H7NO2/c8-7(10)5-3-1-2-4-6(5)9/h1-4,9H,(H2,8,10)
PDB
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Article
PubMed
n/an/an/a>2.50E+7n/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding to stromelysin (MMP-3) in place of acetohydroxamic acid.


J Med Chem 45: 5628-39 (2002)


Article DOI: 10.1021/jm020160g
BindingDB Entry DOI: 10.7270/Q20C4V3M
More data for this
Ligand-Target Pair
Human immunodeficiency virus type 1 integrase


(Human immunodeficiency virus 1)
BDBM50056900
PNG
(2-Carbamoylphenol | 2-Carboxamidophenol | 2-Hydrox...)
Show SMILES NC(=O)c1ccccc1O
Show InChI InChI=1S/C7H7NO2/c8-7(10)5-3-1-2-4-6(5)9/h1-4,9H,(H2,8,10)
PDB
MMDB

B.MOAD
DrugBank
GoogleScholar
AffyNet 
Purchase

CHEMBL
DrugBank
MMDB
PC cid
PC sid
PDB
UniChem

Patents


Similars

Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



National Cancer Institute

Curated by ChEMBL


Assay Description
Inhibition of HIV-1 integrase enzyme by 3'-processing method


J Med Chem 40: 937-41 (1997)


Article DOI: 10.1021/jm960755+
BindingDB Entry DOI: 10.7270/Q2154G4R
More data for this
Ligand-Target Pair