BDBM50057568 4-(3-(trifluoromethyl)-5-(4-(trifluoromethyl)phenyl)-1H-pyrazol-1-yl)benzenesulfonamide::4-[3-Trifluoromethyl-5-(4-trifluoromethyl-phenyl)-pyrazol-1-yl]-benzenesulfonamide::4-[5-(4-trifluoromethylphenyl)-3-trifluoromethyl-1H-pyrazol-1-yl]-benzenesulfonamide::CHEMBL285831

SMILES NS(=O)(=O)c1ccc(cc1)-n1nc(cc1-c1ccc(cc1)C(F)(F)F)C(F)(F)F

InChI Key InChIKey=DVNKXAKWCCJBOO-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50057568   

TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Searle Research And Development

Curated by ChEMBL
LigandPNGBDBM50057568(4-(3-(trifluoromethyl)-5-(4-(trifluoromethyl)pheny...)
Affinity DataIC50: >1.00E+5nMAssay Description:In vitro inhibitory concentration required to block recombinant human prostaglandin G/H synthase 1 (COX-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Astrazeneca R&D MöLndal

Curated by ChEMBL
LigandPNGBDBM50057568(4-(3-(trifluoromethyl)-5-(4-(trifluoromethyl)pheny...)
Affinity DataIC50:  1.70E+4nMAssay Description:Inhibition of recombinant CYP2C9 by fluorescence inhibition assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50057568(4-(3-(trifluoromethyl)-5-(4-(trifluoromethyl)pheny...)
Affinity DataIC50:  8.23E+3nMAssay Description:Inhibitory concentration against human prostaglandin G/H synthase 2 at 25 degrees.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50057568(4-(3-(trifluoromethyl)-5-(4-(trifluoromethyl)pheny...)
Affinity DataIC50:  8.23E+3nMAssay Description:In vitro inhibitory concentration required to block human recombinant prostaglandin G/H synthase 2 (COX-2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed