BDBM50058204 (S)-2-{[6-((R)-2-Amino-3-mercapto-propylamino)-naphthalene-1-carbonyl]-amino}-4-methylsulfanyl-butyric acid::CHEMBL48866::RPR-113829
SMILES CSCC[C@H](NC(=O)c1cccc2cc(NC[C@@H](N)CS)ccc12)C(O)=O
InChI Key InChIKey=YUXOGMIOPNYIQR-DYVFJYSZSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50058204
TargetDimer of Protein farnesyltransferase subunit beta(Homo sapiens (Human))
Centre De Recherches De Vitry-Alfortville
Curated by ChEMBL
Centre De Recherches De Vitry-Alfortville
Curated by ChEMBL
Affinity DataIC50: 17.5nMAssay Description:Inhibition of [3H]-FPP incorporation into human Ki-Ras by farnesyltransferaseMore data for this Ligand-Target Pair
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Indian Institute Of Technology (Bhu)
Curated by ChEMBL
Indian Institute Of Technology (Bhu)
Curated by ChEMBL
Affinity DataIC50: 1.80nMAssay Description:Inhibition of FTase (unknown origin) assessed as reduction in transfer of [3H]FPP to Ha-RasMore data for this Ligand-Target Pair
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Indian Institute Of Technology (Bhu)
Curated by ChEMBL
Indian Institute Of Technology (Bhu)
Curated by ChEMBL
Affinity DataIC50: 17nMAssay Description:Inhibition of FTase (unknown origin) assessed as reduction in transfer of [3H]FPP to Ki-RasMore data for this Ligand-Target Pair
TargetDimer of Protein farnesyltransferase subunit beta(Homo sapiens (Human))
Centre De Recherches De Vitry-Alfortville
Curated by ChEMBL
Centre De Recherches De Vitry-Alfortville
Curated by ChEMBL
Affinity DataIC50: 1.80nMAssay Description:Inhibition of [3H]-FPP incorporation into human Ha-Ras by farnesyltransferaseMore data for this Ligand-Target Pair