BDBM50058577 CHEMBL301645::N-(cyclobutylmethyl)-N-hydroxyurea

SMILES NC(=O)N(O)CC1CCC1

InChI Key InChIKey=VICYWDUJCXUQSR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50058577   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50058577(CHEMBL301645 | N-(cyclobutylmethyl)-N-hydroxyurea)
Affinity DataIC50:  900nMAssay Description:Inhibition of 5-lipoxygenase (5-LO) measured as LTB4 production in human whole blood stimulated with calcium ionophore (A23187).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50058577(CHEMBL301645 | N-(cyclobutylmethyl)-N-hydroxyurea)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibition of 5-lipoxygenase on rat basophil leukemia cell line lysate (RBL-1 2H3 subline) by measuring 5-HETE productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed