BDBM50058763 CHEMBL3335418

SMILES C[C@H]1CN(Cc2ccc(cc2)C(=O)Nc2ccc(cc2)C(F)(F)F)CCN1Cc1cccnc1

InChI Key InChIKey=BAECAPJWZMSHMJ-IBGZPJMESA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50058763   

TargetEndothelial PAS domain-containing protein 1/Hypoxia-inducible factor 1-alpha(Homo sapiens (Human))
Eisai

Curated by ChEMBL

LigandBDBM50058763(CHEMBL3335418)Copy SMILESCopy InChI

Affinity DataIC50:  35nMAssay Description:Inhibition of HIF1 signaling in human U251 cells expressing VEGF by VEGF promoter-driven PLAP reporter gene assayMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI