BDBM50058768 CHEMBL3335413

SMILES FC(F)(F)c1ccc(NC(=O)c2ccc(CN3CCN(Cc4cccnc4)CC3)cc2)cc1

InChI Key InChIKey=CMWPPRIRZXEXDM-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50058768   

TargetEndothelial PAS domain-containing protein 1/Hypoxia-inducible factor 1-alpha(Homo sapiens (Human))
Eisai

Curated by ChEMBL

LigandBDBM50058768(CHEMBL3335413)Copy SMILESCopy InChI

Affinity DataIC50:  14nMAssay Description:Inhibition of HIF1 signaling in human U251 cells expressing VEGF by VEGF promoter-driven PLAP reporter gene assayMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI