BDBM50059016 5'-Methyl-2'-(biphenylmethyl)spiro[cyclopentane-1,7'(8'H)-[3H]imidazo[2,1-b]purin]-4(5'H)-one::CHEMBL303154

SMILES CN1C2=NC3(CCCC3)CN2c2nc(Cc3ccc(cc3)-c3ccccc3)[nH]c2C1=O

InChI Key InChIKey=ZOONDZXUMNNZKJ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50059016   

TargetPhosphodiesterase(Bos taurus)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50059016(5'-Methyl-2'-(biphenylmethyl)spiro[cyclopentane-1,...)
Affinity DataIC50:  2.60E+4nMAssay Description:Inhibitory activity against phosphodiesterase 3 (PDE3) purified from bovine heartMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Banasthali University

Curated by ChEMBL
LigandPNGBDBM50059016(5'-Methyl-2'-(biphenylmethyl)spiro[cyclopentane-1,...)
Affinity DataIC50:  43nMAssay Description:Inhibition of PDE5 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Bos taurus)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50059016(5'-Methyl-2'-(biphenylmethyl)spiro[cyclopentane-1,...)
Affinity DataIC50:  43nMAssay Description:Evaluated for inhibitory activity against Phosphodiesterase 5 (PDE5) purified from bovine lungMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed