BDBM50059249 CHEMBL3393313::US9868720, No. 6

SMILES CCc1ccnc(Nc2cc(nc(C)n2)C2CCCN(C2)C(=O)c2ccccc2)c1

InChI Key InChIKey=BQTLKRXKSBFWID-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50059249   

TargetMitogen-activated protein kinase kinase kinase 12(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM50059249(CHEMBL3393313 | US9868720, No. 6)
Affinity DataKi:  195nMAssay Description:DLK kinase reactions (20 μL) containing 5 nM N-terminally GST-tagged DLK (catalytic domain amino acid 1-520) (Carna Bioscience), 40 nM N-termina...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase 12(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM50059249(CHEMBL3393313 | US9868720, No. 6)
Affinity DataKi:  195nMAssay Description:Inhibition of DLK (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed