BDBM50059583 CHEMBL268818::N-benzyl[D-Pro-10]Dyn A-(1-11)::PhCH2Tyr-Gly-Gly-Phe-Leu-Arg-Arg-lle-Arg-Pro-LysOH

SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccc(O)cc1)NCc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(O)=O

InChI Key InChIKey=SCUDNMPTYPZVCN-RSZDUZASSA-N

Data  8 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50059583   

TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Oregon State University

Curated by ChEMBL
LigandPNGBDBM50059583(CHEMBL268818 | N-benzyl[D-Pro-10]Dyn A-(1-11) | Ph...)
Affinity DataKi:  0.0290nMAssay Description:Affinity against Opioid receptor kappa 1 was determined by measuring the inhibition of [3H]-bremazocine binding to guinea pig cerebellar membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Oregon State University

Curated by ChEMBL
LigandPNGBDBM50059583(CHEMBL268818 | N-benzyl[D-Pro-10]Dyn A-(1-11) | Ph...)
Affinity DataKi:  3.20nMAssay Description:Affinity against Opioid receptor kappa 1 was determined by measuring the inhibition of [3H]U69,593 binding to guinea pig cerebellar membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Rattus norvegicus (rat))
University Of Kansas

Curated by ChEMBL
LigandPNGBDBM50059583(CHEMBL268818 | N-benzyl[D-Pro-10]Dyn A-(1-11) | Ph...)
Affinity DataKi:  14.8nMAssay Description:Displacement of [3H]diprenorphine from rat kappa opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Oregon State University

Curated by ChEMBL
LigandPNGBDBM50059583(CHEMBL268818 | N-benzyl[D-Pro-10]Dyn A-(1-11) | Ph...)
Affinity DataKi:  31.1nMAssay Description:Affinity against Opioid receptor mu 1 was determined by measuring the inhibition of [3H]-DAMGO binding to rat forebrain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Oregon State University

Curated by ChEMBL
LigandPNGBDBM50059583(CHEMBL268818 | N-benzyl[D-Pro-10]Dyn A-(1-11) | Ph...)
Affinity DataKi:  58nMAssay Description:Affinity against Opioid receptor kappa 3 was determined by measuring the inhibition of [3H]-NalBzoH binding to guinea pig cerebellar membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Oregon State University

Curated by ChEMBL
LigandPNGBDBM50059583(CHEMBL268818 | N-benzyl[D-Pro-10]Dyn A-(1-11) | Ph...)
Affinity DataKi:  98.1nMAssay Description:Displacement of [3H]DAMGO from rat mu opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Oregon State University

Curated by ChEMBL
LigandPNGBDBM50059583(CHEMBL268818 | N-benzyl[D-Pro-10]Dyn A-(1-11) | Ph...)
Affinity DataKi:  176nMAssay Description:Affinity against Opioid receptor delta 1 was determined by measuring the inhibition of [3H]-DPDPE binding to rat forebrain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(MOUSE)
University Of Kansas

Curated by ChEMBL
LigandPNGBDBM50059583(CHEMBL268818 | N-benzyl[D-Pro-10]Dyn A-(1-11) | Ph...)
Affinity DataKi:  345nMAssay Description:Displacement of [3H]DPDPE from mouse delta opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Oregon State University

Curated by ChEMBL
LigandPNGBDBM50059583(CHEMBL268818 | N-benzyl[D-Pro-10]Dyn A-(1-11) | Ph...)
Affinity DataIC50:  94nMAssay Description:Binding affinity of the compound towards Opioid receptor kappa 1 using [3H]-diprenorphine as radioligand in guinea pig cerebellar membrane in presenc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Oregon State University

Curated by ChEMBL
LigandPNGBDBM50059583(CHEMBL268818 | N-benzyl[D-Pro-10]Dyn A-(1-11) | Ph...)
Affinity DataIC50:  427nMAssay Description:Affinity against Opioid receptor kappa 2 was determined by measuring the inhibition of [3H]-bremazocine binding to guinea pig cerebellar membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Oregon State University

Curated by ChEMBL
LigandPNGBDBM50059583(CHEMBL268818 | N-benzyl[D-Pro-10]Dyn A-(1-11) | Ph...)
Affinity DataIC50:  7.30nMAssay Description:Binding affinity of the compound towards Opioid receptor kappa 1 using [3H]-diprenorphine as radioligand in guinea pig cerebellar membrane in absence...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed