BDBM50059846 CHEMBL103575::L-745631::[(R)-4-((S)-2-Amino-3-mercapto-propyl)-3-(2-methoxy-ethyl)-piperazin-1-yl]-naphthalen-1-yl-methanone
SMILES COCC[C@@H]1CN(CCN1C[C@H](N)CS)C(=O)c1cccc2ccccc12
InChI Key InChIKey=GKTZPBPAMFCBNI-ZWKOTPCHSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50059846
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Bos taurus (bovine))
Warner-Lambert
Curated by ChEMBL
Warner-Lambert
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Activity against bovine FarnesyltransferaseMore data for this Ligand-Target Pair
TargetGeranylgeranyl transferase type-1 subunit beta/Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Warner-Lambert
Curated by ChEMBL
Warner-Lambert
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Activity against Geranylgeranyl transferase type IMore data for this Ligand-Target Pair
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Mus musculus)
Warner-Lambert
Curated by ChEMBL
Warner-Lambert
Curated by ChEMBL
Affinity DataIC50: 500nMAssay Description:Inhibition of Ras processingMore data for this Ligand-Target Pair