BDBM50059892 2-(6,7-Dimethoxy-2,3-dihydro-benzofuran-4-yl)-ethylamine::CHEMBL102347

SMILES COc1cc(CCN)c2CCOc2c1OC

InChI Key InChIKey=GGGQVCBWGWDHMQ-UHFFFAOYSA-N

Data  8 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50059892   

Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50059892(2-(6,7-Dimethoxy-2,3-dihydro-benzofuran-4-yl)-ethy...)
Affinity DataKi:  118nMAssay Description:Agonist activity at cloned human 5-hydroxytryptamine 2C receptor using [125I]-DOI radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50059892(2-(6,7-Dimethoxy-2,3-dihydro-benzofuran-4-yl)-ethy...)
Affinity DataKi:  311nMAssay Description:Antagonist activity at cloned human 5-hydroxytryptamine 2B receptor using [3H]-rauwolscine radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50059892(2-(6,7-Dimethoxy-2,3-dihydro-benzofuran-4-yl)-ethy...)
Affinity DataKi:  368nMAssay Description:Agonist activity at cloned human 5-hydroxytryptamine 2A receptor using [125I]-DOI radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50059892(2-(6,7-Dimethoxy-2,3-dihydro-benzofuran-4-yl)-ethy...)
Affinity DataKi:  368nMAssay Description:Agonist activity at cloned human 5-hydroxytryptamine 2A receptor using [125I]-DOI radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50059892(2-(6,7-Dimethoxy-2,3-dihydro-benzofuran-4-yl)-ethy...)
Affinity DataKi:  523nMAssay Description:Agonist activity at cloned human 5-hydroxytryptamine 2B receptor using [3H]-5-HT radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50059892(2-(6,7-Dimethoxy-2,3-dihydro-benzofuran-4-yl)-ethy...)
Affinity DataKi:  1.11E+3nMAssay Description:Antagonist activity at cloned human 5-hydroxytryptamine 2C receptor using [3H]-mesulergine radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50059892(2-(6,7-Dimethoxy-2,3-dihydro-benzofuran-4-yl)-ethy...)
Affinity DataKi:  2.50E+3nMAssay Description:Ability to displace [3H]-ketanserin from rat cortical homogenate 5-hydroxytryptamine 2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50059892(2-(6,7-Dimethoxy-2,3-dihydro-benzofuran-4-yl)-ethy...)
Affinity DataKi:  6.20E+3nMAssay Description:Ability to displace [3H]-8-OH-DPAT from rat hippocampal homogenate 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50059892(2-(6,7-Dimethoxy-2,3-dihydro-benzofuran-4-yl)-ethy...)
Affinity DataEC50:  3.00E+3nMAssay Description:Effect on phosphoinositide hydrolysis in NIH 3T3 fibroblast expressing 5-hydroxytryptamine 2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Rattus norvegicus (Rat))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50059892(2-(6,7-Dimethoxy-2,3-dihydro-benzofuran-4-yl)-ethy...)
Affinity DataEC50:  2.00E+3nMAssay Description:Effect on phosphoinositide hydrolysis in NIH 3T3 fibroblast 5-hydroxytryptamine 2C receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed