BDBM50060458 (Z)-7-[(1R,2S,3S,4S)-3-(Naphthalene-2-sulfonylamino)-bicyclo[2.2.1]hept-2-yl]-hept-5-enoic acid::CHEMBL435382

SMILES OC(=O)CCC\C=C/C[C@H]1[C@@H]2CC[C@@H](C2)[C@@H]1NS(=O)(=O)c1ccc2ccccc2c1

InChI Key InChIKey=FIPYJDOEJWQULW-VGQIUGRMSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50060458   

TargetProstaglandin D2 receptor(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50060458((Z)-7-[(1R,2S,3S,4S)-3-(Naphthalene-2-sulfonylamin...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of cAMP formation evoked by the prostaglandin D2 receptor in human plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane A2 receptor(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50060458((Z)-7-[(1R,2S,3S,4S)-3-(Naphthalene-2-sulfonylamin...)
Affinity DataIC50:  0.130nMAssay Description:Inhibition of [3H]- (+)-S-145 specific binding to human platelet membranes in TXA2 receptor (TP) assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50060458((Z)-7-[(1R,2S,3S,4S)-3-(Naphthalene-2-sulfonylamin...)
Affinity DataIC50:  4.90E+3nMAssay Description:Inhibition of [3H]-PGD-2 specific binding to Prostaglandin D2 receptor fromhuman platelet membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstacyclin receptor(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50060458((Z)-7-[(1R,2S,3S,4S)-3-(Naphthalene-2-sulfonylamin...)
Affinity DataIC50:  3.30E+3nMAssay Description:Inhibition of cAMP formation by carbacyclin in Prostaglandin I2 receptor (IP) assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed