BDBM50061298 CHEMBL3393837

SMILES CC1CCN(CC1)c1nc(ccc1CNC(=O)Nc1cccc2cnccc12)C(F)(F)F

InChI Key InChIKey=UVRHQIVWBOGHIJ-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50061298   

TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50061298(CHEMBL3393837)
Affinity DataKi:  0.0200nMAssay Description:Antagonist activity at human TRPV1 assessed as inhibition of NADA-induced effect at 1 uM by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50061298(CHEMBL3393837)
Affinity DataKi:  0.200nMAssay Description:Antagonist activity at human TRPV1 assessed as inhibition of capsaicin-induced effect by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50061298(CHEMBL3393837)
Affinity DataIC50:  0.550nMAssay Description:Antagonist activity at human TRPV1 assessed as inhibition of 45 degC heat-induced effect at 1 uM by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed