BDBM50061436 CHEMBL337835::[4-(8-Chloro-6-hydroxy-5,6-dihydro-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-piperidin-1-yl]-(1-oxy-pyridin-4-yl)-methanone

SMILES [#8]-[#6]-1-[#6]-c2cccnc2\[#6](=[#6]-2/[#6]-[#6]-[#7](-[#6]-[#6]-2)-[#6](=O)-c2cc[n+](-[#8-])cc2)-c2ccc(Cl)cc-12

InChI Key InChIKey=GMPSIMULRVRQRB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50061436   

TargetDimer of Protein farnesyltransferase subunit beta(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50061436(CHEMBL337835 | [4-(8-Chloro-6-hydroxy-5,6-dihydro-...)
Affinity DataIC50:  3.27E+4nMAssay Description:Inhibitory activity against recombinant human farnesyltransferaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed