BDBM50061976 CHEMBL3394320

SMILES CCN(C1CCNCC1)c1cccc2c1C\C=C\CCc1cc(C)[nH]c(=O)c1CNC2=O

InChI Key InChIKey=OKUFKPFKQQFJJN-GQCTYLIASA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50061976   

TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
Therachem Research Medilab (India)

Curated by ChEMBL
LigandPNGBDBM50061976(CHEMBL3394320)
Affinity DataIC50:  200nMAssay Description:Inhibition of methyltransferase activity of EZH2 within human PRC2 complex expressed in Sf9 cells assessed as transfer of tritiated methyl group from...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
Therachem Research Medilab (India)

Curated by ChEMBL
LigandPNGBDBM50061976(CHEMBL3394320)
Affinity DataIC50:  13nMAssay Description:Inhibition of methyltransferase activity of EZH2 within human PRC2 complex expressed in Sf9 cells assessed as transfer of tritiated methyl group from...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed