BDBM50062283 CHEMBL43531::Phosphoric acid mono-[5-(6-amino-2-methylsulfanyl-purin-9-yl)-2-phosphonooxymethyl-tetrahydro-furan-3-yl] ester

SMILES CSc1nc(N)c2ncn(C3CC(OP(O)(O)=O)C(COP(O)(O)=O)O3)c2n1

InChI Key InChIKey=ODAXSQTYAJHMKC-UHFFFAOYSA-N

Data  2 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50062283   

TargetP2Y purinoceptor 1(Meleagris gallopavo)
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50062283(CHEMBL43531 | Phosphoric acid mono-[5-(6-amino-2-m...)
Affinity DataIC50:  2.11E+3nMAssay Description:Antagonist activity at P2Y1 receptor measured as capacity to inhibit 50% of phospholipase C stimulation elicited by 10 nM 2-MeSATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 1(Meleagris gallopavo)
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50062283(CHEMBL43531 | Phosphoric acid mono-[5-(6-amino-2-m...)
Affinity DataEC50:  550nMAssay Description:Concentration at which 50% of the maximal effect (stimulation of PLC at P2Y1 receptor in the turkey erythrocyte membranes) is reachedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 1(Meleagris gallopavo)
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50062283(CHEMBL43531 | Phosphoric acid mono-[5-(6-amino-2-m...)
Affinity DataIC50:  1.89E+3nMAssay Description:In vitro antagonist activity at P2Y1 receptor in turkey erythrocyte membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 1(Meleagris gallopavo)
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50062283(CHEMBL43531 | Phosphoric acid mono-[5-(6-amino-2-m...)
Affinity DataEC50:  550nMAssay Description:Agonist activity at P2Y1 receptor measured as capacity to stimulate 50% phospholipase C in turkey erythrocyte membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed