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BDBM50062291 CHEMBL54116::Phosphoric acid mono-[2-(6-methylamino-purin-9-yl)-5-phosphonooxymethyl-tetrahydro-furan-3-yl] ester

InChI string: InChI=1S/C11H17N5O9P2/c1-12-9-8-10(14-4-13-9)16(5-15-8)11-7(25-27(20,21)22)2-6(24-11)3-23-26(17,18)19/h4-7,11H,2-3H2,1H3,(H,12,13,14)(H2,17,18,19)(H2,20,21,22)

SMILES: CNc1ncnc2n(cnc12)C1OC(COP(O)(O)=O)CC1OP(O)(O)=O

InChI Key: InChIKey=IZSBZSQDVKIOPM-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50062291   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
P2Y purinoceptor 1


(Meleagris gallopavo)
BDBM50062291
PNG
(CHEMBL54116 | Phosphoric acid mono-[2-(6-methylami...)
Show SMILES CNc1ncnc2n(cnc12)C1OC(COP(O)(O)=O)CC1OP(O)(O)=O
Show InChI InChI=1S/C11H17N5O9P2/c1-12-9-8-10(14-4-13-9)16(5-15-8)11-7(25-27(20,21)22)2-6(24-11)3-23-26(17,18)19/h4-7,11H,2-3H2,1H3,(H,12,13,14)(H2,17,18,19)(H2,20,21,22)
MMDB

KEGG

UniProtKB/SwissProt

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PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 324n/an/an/an/an/an/a



National Institute of Diabetes

Curated by ChEMBL


Assay Description
Antagonist activity at P2Y1 receptor measured as capacity to inhibit 50% of phospholipase C stimulation elicited by 10 nM 2-MeSATP


J Med Chem 41: 183-90 (1998)

More data for this
Ligand-Target Pair