BDBM50062369 CHEMBL3397287
SMILES COc1cc(C)cc(c1)-c1nn(CC#N)cc1-c1cc(NCCN2CCOCC2)nc(n1)-c1cccnc1
InChI Key InChIKey=BUFPQXRLSMHRJW-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50062369
TargetProto-oncogene tyrosine-protein kinase ROS(Homo sapiens (Human))
Korea University Of Science And Technology
Curated by ChEMBL
Korea University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 5.76E+4nMAssay Description:Inhibition of ROS1 in human HCC78 cells after 48 hrs by CellTitre-Glo assayMore data for this Ligand-Target Pair
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Korea University Of Science And Technology
Curated by ChEMBL
Korea University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 1.02E+4nMAssay Description:Inhibition of ALK (unknown origin) incubated for 20 mins followed by [33P]ATP addition measured after 120 mins by HotSpot assayMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase ROS(Homo sapiens (Human))
Korea University Of Science And Technology
Curated by ChEMBL
Korea University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 148nMAssay Description:Inhibition of ROS1 (unknown origin) incubated for 20 mins followed by [33P]ATP addition measured after 120 mins by HotSpot assayMore data for this Ligand-Target Pair