BDBM50062661 2-Chloro-4-trifluoromethyl-pyrimidine-5-carboxylic acid (3,5-dichloro-phenyl)-amide::CHEMBL334485

SMILES FC(F)(F)c1nc(Cl)ncc1C(=O)Nc1cc(Cl)cc(Cl)c1

InChI Key InChIKey=NLRGWKVQZPYNNM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50062661   

TargetNuclear factor NF-kappa-B p105 subunit(Homo sapiens (Human))
Signal Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50062661(2-Chloro-4-trifluoromethyl-pyrimidine-5-carboxylic...)
Affinity DataIC50:  500nMAssay Description:In vitro inhibitory activity against human Jurkat T-Cells stably transfected with an Nuclear factor kappa B transcription factorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclic AMP-dependent transcription factor ATF-1(Homo sapiens (Human))
Signal Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50062661(2-Chloro-4-trifluoromethyl-pyrimidine-5-carboxylic...)
Affinity DataIC50:  500nMAssay Description:In vitro inhibitory activity against human Jurkat T-Cells stably transfected with activating transcription factor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed