BDBM50063723 2-(2-Iodo-phenylamino)-7-methyl-benzo[d][1,3]oxazin-4-one::CHEMBL10248

SMILES Cc1ccc2c(c1)nc(Nc1ccccc1I)oc2=O

InChI Key InChIKey=AAGGENJJHKGQRB-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50063723   

TargetComplement C1r subcomponent(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50063723(2-(2-Iodo-phenylamino)-7-methyl-benzo[d][1,3]oxazi...)
Affinity DataIC50:  1.50E+3nMAssay Description:50% inhibition of human C1r serine protease after 60 mins using CbzGly-Arg-S-Bzl as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetComplement C1r subcomponent(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50063723(2-(2-Iodo-phenylamino)-7-methyl-benzo[d][1,3]oxazi...)
Affinity DataIC50:  800nMAssay Description:Inhibition of 50% of human C1r Serine Protease by initially using CbzGly-Arg-S-Bzl as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50063723(2-(2-Iodo-phenylamino)-7-methyl-benzo[d][1,3]oxazi...)
Affinity DataIC50: >1.00E+5nMAssay Description:Concentration of compound required to inhibit 50% trypsin derived from bovine pancreasMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed