BDBM50064340 (2R,3S)-N*4*-Hydroxy-2-isobutyl-N*1*-[(R)-2-(4-methoxy-phenyl)-1-methylcarbamoyl-ethyl]-3-methyl-succinamide::(2R,3S)-N*4*-Hydroxy-2-isobutyl-N*1*-[(S)-2-(4-methoxy-phenyl)-1-methylcarbamoyl-ethyl]-3-methyl-succinamide::BB-16::CHEMBL417537::N*4*-Hydroxy-2-isobutyl-N*1*-[2-(4-methoxy-phenyl)-1-methylcarbamoyl-ethyl]-3-methyl-succinamide
SMILES CNC(=O)[C@@H](Cc1ccc(OC)cc1)NC(=O)[C@H](CC(C)C)[C@H](C)C(=O)NO
InChI Key InChIKey=XDJHCLNLKWGZCM-IAOVAPTHSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 50064340
Affinity DataKi: 0.130nMAssay Description:Inhibition of MMP-9 (Matrix metalloproteinase-9)More data for this Ligand-Target Pair
Affinity DataKi: 0.870nMAssay Description:Inhibition of MMP-1 (Matrix metalloproteinase-1)More data for this Ligand-Target Pair
Affinity DataKi: <1nMAssay Description:In vitro inhibition of human MMP-1.More data for this Ligand-Target Pair
Affinity DataKi: <1nMAssay Description:In vitro inhibition of human MMP-9.More data for this Ligand-Target Pair
Affinity DataKi: 1.90nMAssay Description:Inhibition of human MMP-3.More data for this Ligand-Target Pair
Affinity DataKi: 1.93nMAssay Description:Inhibition of MMP-3 (Matrix metalloproteinase-3)More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Dupont Pharmaceuticals
Curated by ChEMBL
Dupont Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of LPS-stimulated TNF-alpha release in human whole bloodMore data for this Ligand-Target Pair