BDBM50064341 (6S,7R,10S)-7-Isobutyl-8-oxo-2-oxa-9-aza-bicyclo[10.2.2]hexadeca-1(15),12(16),13-triene-6,10-dicarboxylic acid 6-hydroxyamide 10-methylamide::7-Isobutyl-8-oxo-2-oxa-9-aza-bicyclo[10.2.2]hexadeca-1(15),12(16),13-triene-6,10-dicarboxylic acid 6-hydroxyamide 10-methylamide (SE205)::CHEMBL45631
SMILES CNC(=O)[C@@H]1Cc2ccc(OCCC[C@@H]([C@@H](CC(C)C)C(=O)N1)C(=O)NO)cc2
InChI Key InChIKey=USEJKZYMWYHGSP-KSZLIROESA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 11 hits for monomerid = 50064341
Affinity DataKi: 1.20nMAssay Description:In vitro inhibition of human MMP-1.More data for this Ligand-Target Pair
Affinity DataKi: 1.20nMAssay Description:Inhibition of MMP-1 (Matrix metalloproteinase-1)More data for this Ligand-Target Pair
Affinity DataKi: 1.80nMAssay Description:In vitro inhibition of human MMP-9.More data for this Ligand-Target Pair
Affinity DataKi: 1.80nMAssay Description:Inhibition of MMP-9 (Matrix metalloproteinase-9)More data for this Ligand-Target Pair
Affinity DataKi: 32.7nMAssay Description:Inhibition of MMP-3 (Matrix metalloproteinase-3)More data for this Ligand-Target Pair
Affinity DataKi: 33nMAssay Description:Inhibition of human MMP-3.More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of fibroblast collagenase (MMP-1)More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Dupont Pharmaceuticals
Curated by ChEMBL
Dupont Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of LPS-stimulated TNF-alpha release in human whole bloodMore data for this Ligand-Target Pair
Affinity DataIC50: 2.60nMAssay Description:Inhibition of fibroblast gelatinase A (MMP-2)More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of fibroblast matrilysin (MMP-7)More data for this Ligand-Target Pair
Affinity DataIC50: 7.80nMAssay Description:Inhibition of fibroblast stromelysin (MMP-3)More data for this Ligand-Target Pair