BDBM50064392 CHEMBL3403716

SMILES Cc1c2CCOc3cc(ccc3-n2c2CC(C)(C)CC(=O)c12)C(N)=O

InChI Key InChIKey=CXFXSTHDYJQJAP-UHFFFAOYSA-N

Data  1 KI

PDB links: 1 PDB ID matches this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50064392   

TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Vertex Pharmaceuticals

Curated by ChEMBL

LigandBDBM50064392(CHEMBL3403716)Copy SMILESCopy InChI

Affinity DataKi:  86nMAssay Description:Inhibition of FITC-GA binding to Hsp90alpha (unknown origin) ATPase site after 2 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidPDBSimilars

In DepthDetails ArticlePubMedPDB3D Structure (crystal)
Copy BDB DOI