BDBM50065457 EMD-1214063::MSC-2156119::MSC-2156119J::Tepotinib::US9403799, A14
SMILES CN1CCC(COc2cnc(nc2)-c2cccc(Cn3nc(ccc3=O)-c3cccc(c3)C#N)c2)CC1
InChI Key InChIKey=AHYMHWXQRWRBKT-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 12 hits for monomerid = 50065457
Affinity DataIC50: <100nMT: 25°CAssay Description:The test plates used are 96-well Flashplate® microtitre plates from Perkin Elmer (Cat. No. SMP200). The components of the kinase reaction describ...More data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataIC50: <100nMT: 25°CAssay Description:The test plates used are 96-well Flashplate® microtitre plates from Perkin Elmer (Cat. No. SMP200). The components of the kinase reaction describ...More data for this Ligand-Target Pair
Affinity DataIC50: <100nMT: 25°CAssay Description:The test plates used are 96-well Flashplate® microtitre plates from Perkin Elmer (Cat. No. SMP200). The components of the kinase reaction describ...More data for this Ligand-Target Pair
Affinity DataIC50: <100nMT: 25°CAssay Description:The test plates used are 96-well Flashplate® microtitre plates from Perkin Elmer (Cat. No. SMP200). The components of the kinase reaction describ...More data for this Ligand-Target Pair
Affinity DataIC50: <100nMT: 25°CAssay Description:The test plates used are 96-well Flashplate® microtitre plates from Perkin Elmer (Cat. No. SMP200). The components of the kinase reaction describ...More data for this Ligand-Target Pair
Affinity DataIC50: 3.10nMAssay Description:Inhibition of N-terminal His/SUMO tagged wild type human c-Met (1038 to 1346 residues) transfected in Escherichia coli using Tyr06 peptide as substra...More data for this Ligand-Target Pair
Affinity DataIC50: <100nMT: 25°CAssay Description:The test plates used are 96-well Flashplate® microtitre plates from Perkin Elmer (Cat. No. SMP200). The components of the kinase reaction describ...More data for this Ligand-Target Pair
Affinity DataIC50: <100nMT: 25°CAssay Description:The test plates used are 96-well Flashplate® microtitre plates from Perkin Elmer (Cat. No. SMP200). The components of the kinase reaction describ...More data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Inhibition of c-Met kinase in human A549 cells assessed as inhibition of phosphorylation after 45 mins by electrochemiluminescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: <1nMAssay Description:Inhibition of GST-His6-tagged recombinant human c-Met kinase domain (956 to 1390) after 60 mins by anoff-chip mobility shift assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of c-Met (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: <100nMT: 25°CAssay Description:The test plates used are 96-well Flashplate® microtitre plates from Perkin Elmer (Cat. No. SMP200). The components of the kinase reaction describ...More data for this Ligand-Target Pair