BDBM50065486 CHEMBL3402759

SMILES COc1cccc(c1)-c1ccc(=O)n(Cc2cccc(c2)-c2ncc(OCCCN(C)C)cn2)n1

InChI Key InChIKey=RTKBHBAMZLAVKQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50065486   

TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50065486(CHEMBL3402759)
Affinity DataIC50:  5.70nMAssay Description:Inhibition of GST-His6-tagged recombinant human c-Met kinase domain (956 to 1390) after 60 mins by anoff-chip mobility shift assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50065486(CHEMBL3402759)
Affinity DataIC50:  200nMAssay Description:Inhibition of c-Met kinase in human A549 cells assessed as inhibition of phosphorylation after 45 mins by electrochemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed