BDBM50067268 4-{(E)-2-[({[3-(2-Methoxymethyl-1-methyl-1H-benzoimidazol-4-yloxymethyl)-2,4-dimethyl-phenyl]-methyl-carbamoyl}-methyl)-carbamoyl]-vinyl}-N-methyl-benzamide::CHEMBL298320

SMILES CNC(=O)c1ccc(\C=C\C(=O)NCC(=O)N(C)c2ccc(C)c(COc3cccc4n(C)c(COC)nc34)c2C)cc1

InChI Key InChIKey=XEKXLZMTJOGXDK-GHRIWEEISA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50067268   

TargetB2 bradykinin receptor(Cavia porcellus)
Fujisawa Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50067268(4-{(E)-2-[({[3-(2-Methoxymethyl-1-methyl-1H-benzoi...)
Affinity DataIC50:  1.00E+3nMAssay Description:Concentration required to inhibit specific binding of [ 3H]BK (0.06 nM) to Bradykinin receptor B2 in guinea pig ileum membrane preparations by 50%.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetB2 bradykinin receptor(Homo sapiens (Human))
Fujisawa Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50067268(4-{(E)-2-[({[3-(2-Methoxymethyl-1-methyl-1H-benzoi...)
Affinity DataIC50:  1.00E+3nMAssay Description:In vitro inhibitory activity towards bradykinin receptor B2 using [3H]BK (0.06 nM) as a radioligand in guinea pig ileum membrane preparationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetB2 bradykinin receptor(Homo sapiens (Human))
Fujisawa Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50067268(4-{(E)-2-[({[3-(2-Methoxymethyl-1-methyl-1H-benzoi...)
Affinity DataIC50:  9.10E+3nMAssay Description:In vitro inhibitory activity towards human bradykinin receptor B2 expressed in CHO cells using [3H]BK (1.0 nM) as a radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetB2 bradykinin receptor(Homo sapiens (Human))
Fujisawa Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50067268(4-{(E)-2-[({[3-(2-Methoxymethyl-1-methyl-1H-benzoi...)
Affinity DataIC50:  1.00E+3nMAssay Description:Concentration required to inhibit specific binding of [ 3H]BK (0.06 nM) to Bradykinin receptor B2 in guinea pig ileum membrane preparations by 50%.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed