BDBM50067895 CHEMBL140780::Tolyl boronic acid::p-tolylboronic acid

SMILES Cc1ccc(cc1)B(O)O

InChI Key InChIKey=BIWQNIMLAISTBV-UHFFFAOYSA-N

Data  4 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50067895   

TargetBeta-lactamase(Escherichia coli)
Northwestern University Medical School

Curated by ChEMBL
LigandPNGBDBM50067895(CHEMBL140780 | Tolyl boronic acid | p-tolylboronic...)
Affinity DataKi:  5.40E+3nMAssay Description:Inhibitory activity against E. coli AmpC beta-lactamase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase(Candida albicans (Yeast))
Universit£

Curated by ChEMBL
LigandPNGBDBM50067895(CHEMBL140780 | Tolyl boronic acid | p-tolylboronic...)
Affinity DataKi:  9.00E+3nMAssay Description:Inhibition of Candida albicans recombinant Carbonic anhydrase preincubated for 15 mins by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50067895(CHEMBL140780 | Tolyl boronic acid | p-tolylboronic...)
Affinity DataKi:  1.08E+4nMAssay Description:Inhibition of human recombinant cytosolic carbonic anhydrase 2 preincubated for 15 mins by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50067895(CHEMBL140780 | Tolyl boronic acid | p-tolylboronic...)
Affinity DataKi:  2.78E+5nMAssay Description:Inhibition of human recombinant cytosolic carbonic anhydrase 1 preincubated for 15 mins by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelial lipase(Homo sapiens (Human))
Tufts University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50067895(CHEMBL140780 | Tolyl boronic acid | p-tolylboronic...)
Affinity DataIC50:  2.20E+4nMAssay Description:Inhibition of human endothelial lipase overexpressed in HUVEC cells using bis-BD-PC and mono-BD-TG as substrate incubated for 10 mins prior to substr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelial lipase(Homo sapiens (Human))
Tufts University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50067895(CHEMBL140780 | Tolyl boronic acid | p-tolylboronic...)
Affinity DataIC50:  1.70E+4nMAssay Description:Inhibition of human endothelial lipase expressed using recombinant adenovirus using glycerol-tri[9,10(n)-3H]oleate after 1 hr by vesicle assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLipoprotein lipase(Homo sapiens (Human))
Tufts University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50067895(CHEMBL140780 | Tolyl boronic acid | p-tolylboronic...)
Affinity DataIC50:  9.00E+3nMAssay Description:Inhibition of human lipoprotein lipase expressed using recombinant adenovirus using glycerol-tri[9,10(n)-3H]oleate after 1 hr by vesicle assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLipoprotein lipase(Homo sapiens (Human))
Tufts University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50067895(CHEMBL140780 | Tolyl boronic acid | p-tolylboronic...)
Affinity DataIC50:  2.50E+4nMAssay Description:Inhibition of human lipoprotein lipase expressed in HEK293 cells using bis-BD-PC and mono-BD-TG as substrate incubated for 10 mins prior to substrate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed