BDBM50068452 1-[2-(3,4-Dichloro-phenyl)-ethyl]-4-(3-phenyl-propyl)-piperazine::CHEMBL343654

SMILES Clc1ccc(CCN2CCN(CCCc3ccccc3)CC2)cc1Cl

InChI Key InChIKey=MXPILNNLSULRSB-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50068452   

TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50068452(1-[2-(3,4-Dichloro-phenyl)-ethyl]-4-(3-phenyl-prop...)
Affinity DataKi:  2.20nMAssay Description:Binding affinity was tested against sigma-1 receptor in guinea brain membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
University Of Missouri

Curated by ChEMBL
LigandPNGBDBM50068452(1-[2-(3,4-Dichloro-phenyl)-ethyl]-4-(3-phenyl-prop...)
Affinity DataKi:  2.20nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane after 150 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(MOUSE)
University Of Missouri

Curated by ChEMBL
LigandPNGBDBM50068452(1-[2-(3,4-Dichloro-phenyl)-ethyl]-4-(3-phenyl-prop...)
Affinity DataKi:  2.87E+3nMAssay Description:Displacement of [3H]paroxetine from mouse SERT in whole brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(MOUSE)
University Of Missouri

Curated by ChEMBL
LigandPNGBDBM50068452(1-[2-(3,4-Dichloro-phenyl)-ethyl]-4-(3-phenyl-prop...)
Affinity DataKi:  8.20E+3nMAssay Description:Displacement of [3H]RTI-121 from mouse DAT in striatal membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed