BDBM50068675 4'-Isobutyl-biphenyl-2-sulfonic acid (4,5,6,7-tetrahydro-benzo[c]isoxazol-3-yl)-amide::CHEMBL148757

SMILES CC(C)Cc1ccc(cc1)-c1ccccc1S(=O)(=O)Nc1onc2CCCCc12

InChI Key InChIKey=PNIMKAGRLWRIQD-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50068675   

TargetEndothelin-1 receptor(RAT)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50068675(4'-Isobutyl-biphenyl-2-sulfonic acid (4,5,6,7-tetr...)
Affinity DataKi:  2.40E+4nMAssay Description:Ability to inhibit binding of [125I]ET1 to membranes prepared from A10 rat thoracic aorta smooth muscle Endothelin A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(RAT)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50068675(4'-Isobutyl-biphenyl-2-sulfonic acid (4,5,6,7-tetr...)
Affinity DataKi: >2.00E+5nMAssay Description:Ability to inhibit binding of [125I]-ET-1 to membranes prepared from A10 rat cerebellum (Endothelin B receptor)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed