BDBM50068733 4'-(Propane-2-sulfonyl)-biphenyl-2-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide::CHEMBL149050

SMILES CC(C)S(=O)(=O)c1ccc(cc1)-c1ccccc1S(=O)(=O)Nc1onc(C)c1C

InChI Key InChIKey=BACQXHYPRKBLQD-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50068733   

TargetEndothelin-1 receptor(RAT)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50068733(4'-(Propane-2-sulfonyl)-biphenyl-2-sulfonic acid (...)
Affinity DataKi:  110nMAssay Description:Ability to inhibit binding of [125I]ET1 to membranes prepared from A10 rat thoracic aorta smooth muscle Endothelin A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(RAT)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50068733(4'-(Propane-2-sulfonyl)-biphenyl-2-sulfonic acid (...)
Affinity DataKi:  1.70E+5nMAssay Description:Ability to inhibit binding of [125I]-ET-1 to membranes prepared from A10 rat cerebellum (Endothelin B receptor)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed