BDBM50069631 CHEMBL3402520

SMILES CC(C)C1=C(SC2=N[C@](C)([C@H](N12)c1ccc(Cl)c(F)c1)c1ccc(Cl)nc1)C(=O)N1C[C@H](F)C[C@H]1C(=O)N1CC2(CC2)NC[C@@H]1C

InChI Key InChIKey=OKIDBNYMCUVSLU-QSSUNTQZSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50069631   

TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50069631(CHEMBL3402520)
Affinity DataIC50:  2.20nMAssay Description:Binding affinity to GST-tagged MDM2 (unknown origin) assessed as inhibition of interaction with His-tagged p53 after 1 hr by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed