BDBM50069632 CHEMBL3402521

SMILES CC[C@@H]1CNC2(CC2)CN1C(=O)[C@@H]1C[C@@H](F)CN1C(=O)C1=C(C(C)C)N2[C@H](c3ccc(Cl)c(F)c3)[C@@](C)(N=C2S1)c1ccc(Cl)nc1

InChI Key InChIKey=QUYOIFDRHGZSFZ-YABFKZQLSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50069632   

TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50069632(CHEMBL3402521)
Affinity DataIC50:  2.40nMAssay Description:Binding affinity to GST-tagged MDM2 (unknown origin) assessed as inhibition of interaction with His-tagged p53 after 1 hr by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed