BDBM50069913 CHEMBL101910::N-(2-Fluoro-5-{2-[(thiophen-2-ylmethyl)-amino]-ethoxy}-phenyl)-methanesulfonamide

SMILES CS(=O)(=O)Nc1cc(OCCNCc2cccs2)ccc1F

InChI Key InChIKey=ORNYDPYZWVONOG-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50069913   

TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Wyeth-Ayerst Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50069913(CHEMBL101910 | N-(2-Fluoro-5-{2-[(thiophen-2-ylmet...)
Affinity DataKi:  12nMAssay Description:Antagonistic activity towards dopamine D2 receptor using radioligand [3H]-spiperone in rat striatal membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Wyeth-Ayerst Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50069913(CHEMBL101910 | N-(2-Fluoro-5-{2-[(thiophen-2-ylmet...)
Affinity DataKi:  20nMAssay Description:Agonistic activity towards dopamine D2 receptor using radioligand [3H]-quinpirole in rat striatal membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Wyeth-Ayerst Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50069913(CHEMBL101910 | N-(2-Fluoro-5-{2-[(thiophen-2-ylmet...)
Affinity DataKi: >300nMAssay Description:Binding affinity towards human cloned dopamine (hD2s) receptors expressed in CHO cell membranes using [3H]-spiperoneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Wyeth-Ayerst Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50069913(CHEMBL101910 | N-(2-Fluoro-5-{2-[(thiophen-2-ylmet...)
Affinity DataKi: >400nMAssay Description:Binding affinity towards human cloned Dopamine receptor D4.4 expressed in CHO cells using [3H]-spiperone as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Wyeth-Ayerst Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50069913(CHEMBL101910 | N-(2-Fluoro-5-{2-[(thiophen-2-ylmet...)
Affinity DataKi: >400nMAssay Description:Binding affinity towards human cloned dopamine (hD3) receptor expressed in CHO cells using [3H]-spiperone as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed