BDBM50071394 5-Cyclopropyl-isoxazole-4-carbothioic acid (4-trifluoromethyl-phenyl)-amide::CHEMBL70708

SMILES FC(F)(F)c1ccc(NC(=S)c2cnoc2C2CC2)cc1

InChI Key InChIKey=NIFLXVUORSUDQV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50071394   

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50071394(5-Cyclopropyl-isoxazole-4-carbothioic acid (4-trif...)
Affinity DataIC50:  3.20E+3nMAssay Description:Immunosuppressive activity of the compound expressed as ability to inhibit human recombinant dihydroorotate dehydrogenase (DHODH)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed