BDBM50071701 1-[4-(8-Chloro-5,11-dihydro-10-thia-4-aza-dibenzo[a,d]cyclohepten-5-yl)-piperazin-1-yl]-2-piperidin-4-yl-ethanone::CHEMBL85564

SMILES Clc1ccc2C(N3CCN(CC3)C(=O)CC3CCNCC3)c3ncccc3CSc2c1

InChI Key InChIKey=URIAEERZIAFNMX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50071701   

TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50071701(1-[4-(8-Chloro-5,11-dihydro-10-thia-4-aza-dibenzo[...)
Affinity DataIC50:  1.10E+3nMAssay Description:In vitro FPT potency by measuring the ability to inhibit the transfer of [3H]-farnesyl from farnesyl pyrophosphate to H-Ras-CLVS.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed