BDBM50071701 1-[4-(8-Chloro-5,11-dihydro-10-thia-4-aza-dibenzo[a,d]cyclohepten-5-yl)-piperazin-1-yl]-2-piperidin-4-yl-ethanone::CHEMBL85564
SMILES Clc1ccc2C(N3CCN(CC3)C(=O)CC3CCNCC3)c3ncccc3CSc2c1
InChI Key InChIKey=URIAEERZIAFNMX-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 50071701
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataIC50: 1.10E+3nMAssay Description:In vitro FPT potency by measuring the ability to inhibit the transfer of [3H]-farnesyl from farnesyl pyrophosphate to H-Ras-CLVS.More data for this Ligand-Target Pair